A novel method for producing solid polymer microneedles using laser ablated moulds in an injection moulding process

A scalable fabrication process of polymer microneedles

While polymer microneedles may easily be fabricated by casting a solution in a mold, either centrifugation or vacuumizing is needed to pull the viscous polymer solution into the microholes of the mold. We report a novel process to fabricate polymer microneedles with a one-sided vacuum using a ceramic mold that is breathable but water impermeable. A polymer solution containing polyvinyl alcohol ...

A Model of the Injection Moulding Process

This paper is concerned with the injection moulding process, in which hot molten plastic is injected under high pressure into a thin cold mould. Assuming that the velocity and temperature profiles across the mould maintain their shape, a simple steady state model to describe the behaviour of a Newtonian fluid during the rilling stage is developed. Various phenomena of the process are examined, ...

Micro-Injection Moulding of Polymer Microfluidic Devices

* Building 56, Cranfield University, Wharley End, Cranfield, Bedfordshire, MK43 0AL, UK. Tel: +44 (0)1234 750111 ext: 2513; E-mail: [email protected] a Building 56, Cranfield University, Wharley End, Cranfield, Bedfordshire, MK43 0AL, UK. Fax: +44 (0)1234 751346; Tel: +44 (0)1234 750111 ext: 2379; E-mail: [email protected] b Building 61, Cranfield University, Wharley End, Cranfield...

Injection Moulding of Solid Oral Dosage Forms

Oral solid dosage forms are the most patient-accepted and therefore industrially relevant pharmaceutical applications, representing 80% of the market share. In that context, polymer processing techniques, such as hot melt extrusion (HME) or injection molding (IM), are increasingly used to process primary material into the final dosage forms due to several benefits (e.g., enhanced solubility or ...

Strategies for high quality injection moulding of polymer nanopillars